A blaze that swept through a dogs home has now claimed the lives of 60 animals, with the death toll expected to rise further.
More than 150 dogs were rescued from the fire, which broke out at Manchester Dogs' Home in Moss Brook Road in Harpurhey on Thursday evening.
A 15-year-old boy has been arrested on suspicion of arson.
A JustGiving account set up by the Manchester Evening News has raised £223,000 in the space of 12 hours.
The number of dogs initially confirmed to have died in the fire was 43.
Firefighters said the 150 dogs rescued from the blaze have been moved to Cheshire Dogs' Home.
'Angry and upset'A statement from the home said: "The staff and trustees of Cheshire Dogs' Home near Warrington would like to express their enormous gratitude for the huge support received from the public following the devastating fire at its sister site Manchester Dogs' Home last night."
Hundreds of messages of sympathy have been left on the JustGiving page, as the amount of money donated continues to rise.
Julie Fowler wrote: "Thinking of all staff and dogs, RIP to those who didn't make it."
Julie Eccleston posted: "From here all I can do is donate money. Bless you, local people, for helping out."
Greater Manchester Fire and Rescue Service (GMFRS) tweeted their thanks to people who had donated cash, saying: "One hundred and fifty dogs rescued. Thousands of pounds donated. Thank you Greater Manchester."
Det Insp Neil Jones, of Greater Manchester Police, said: "The response from the public has been overwhelming and this is clearly an incident that has tugged on the heartstrings of many.
"A number of people, including police officers and staff were quickly on the scene and put their life on the line to help with the rescue effort.
"We are determined to establish exactly how and why this fire started and will be working closely with our partners from the fire service.
"Anyone wanting to donate items such as food and blankets can do so by bringing them to the north Manchester police headquarters."
Supt Marcus Noden, of GMFRS, said: "We are in the very early stages of the investigation and have a young boy in custody, however we would ask if anyone was in the area and remembers seeing anything suspicious around the dogs' home that they call police and tell us what they know.
"As a dog owner myself I understand that many people will feel angry and upset about what has happened, but I would ask that they let the police carry out their investigations and not take matters into their own hands."
The Manchester home was established in 1893 and cares for more than 7,000 dogs every year.
It is run entirely on donations from the general public.
Are you in Harpurhey? Did you see the fire on Thursday evening? Email your pictures to haveyoursay@bbc.co.uk.
Send your pictures and videos to yourpics@bbc.co.uk or text them to 61124 (UK) or +44 7624 800 100 (International). If you have a large file you can upload here.
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