MPs are expected to approve the introduction of standardised packaging for cigarettes in England later.
If passed, it will mean from 2016 every packet will look the same except for the make and brand name, with graphic photos accompanying health warnings.
The Welsh government has said it will follow suit while Northern Ireland and Scotland are also considering the move.
The Irish Republic passed a similar law earlier this month and Australia has had plain packaging since 2012.
Westminster's move follows a series of public consultations on the issue.
A review set up by the government and carried out by by paediatrician Sir Cyril Chantler concluded last year it was very likely the change would lead to a modest but important reduction in the uptake and prevalence of smoking.
Research has shown standardised packaging makes the packets less appealing and helps reinforce health messages.
Meanwhile, darker colours - olive green is proposed - are favoured ahead of white, as this is perceived to signify more harm.
Health campaigners have long been pushing for the move, saying it will help save lives.
But the Tobacco Manufacturer's Association has argued there is a "complete lack of evidence that the policy will work".
Stubbing smoking out: A history of legislation in the UK- 1965: Government bans cigarette advertising on television
- 1971: Ministers announce health warnings to be carried on all cigarette packets
- 1984: Smoking banned on London underground trains
- 2002: Legislation passed banning tobacco advertising, promotion and sponsorship
- 2005: Smoking banned on all trains
- 2006: A ban on smoking in public places, including bars and restaurants, comes into effect in Scotland
- 2007: England, Wales and Northern Ireland introduce their own bans on smoking in public places
- 2008: Picture health warnings introduced on cigarette packets
- 2012: Large shops are banned from displaying cigarettes. Smaller shops to follow suit in 2015
- 2015: MPs vote in favour of banning smoking in cars where children are present
While most MPs are expected to back the move, there have been concerns raised about how the process is being handled.
Powers for standardising packaging were in the Children and Families Act 2014, but the Commons must approve bringing them into force.
The regulations were discussed and agreed by a committee earlier this week and will now be subject to a free vote on the floor of the House.
But as they are not primary legislation, there will be no further debate.
Conservative MP Nick De Bois said: "I certainly would never have expected to see this measure before this House this late in the parliament, announced in an adjournment debate without the benefit of a full debate."
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